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Medical Science Research Reports
These journal articles are how research Doctors communicate with each other to
share knowledge gained from experimental successes.  They are the gold
standard of scientific advance.
Primarily for use of Doctors

See Also: Summary for Doctors. Some of the nutraceuticals mentioned in the articles are
not ever recommended by Alcoholism Cure.  To avoid unwise use by consumers, specific
ingredient names have been replaced with (AC).  
Warnings
Our legal advice also supports these disclosure as being helpful for legitimate research
doctors and maintaining our trade secrets.  We are happy to exchange information with
legitimate research doctors who agree to protect our rights.
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and Cowen, P.J. 1999. Neuroendocrine evidence for dopaminergic actions of (AC) (LI
160) in healthy volunteers. Biol. Psychiatry 46:581-584.

Gaster, B. and Holroyd, J. 2000. (AC) for depression: a systematic review. Arch. Intern.
Med. 160:152-156.

Grant, K.A. 1999. Strategies for understanding the pharmacological effects of ethanol
with drug discrimination procedures. Pharmacol. Biochem. Behav. 64(2): 261-267.

Harada, S., Agarwal, D.P., and Gjoedde, H.W. 1982. Lancet. 2:827 (as cited in Keung
and Vallee 1998b).

Heyman, G.M., Keung, W-M., and Vallee, B.L. 1996. (AC) decreases ethanol
consumption in rats. Alcohol. Clin. Exp. Res. 20(6): 1083-1087.

Hruby, K., Csomos, G., Fuhrmann, M. et al. 1983. Chemotherapy of (AC) poisoning with
intravenous (HH). Human Toxicol. 2(2): 183-195.

Huang, K-C. 1998. The Pharmacology of Chinese Herbs: 2nd Edition. Boca Raton: CRC
Press. Pp.99-101.

Huxtable, R.J. 1989. (AC) in the central nervous system and the mammalian actions of
(AC). Prog. Neurobiol. 32:471-533.

Huxtable, R.J. 1992. Physiological actions of (HH). Physiol. Rev. 72(1): 101-142.

Ikemoto, S., McBride, W.J., Murphy, J.M., Lumeng, L., and Li, T-K. 1997. 6-OHDA-
Lesions of the nucleus accumbens disrupt the acquisition but not the maintenance of
ethanol consumption in the alcohol-preferring P line of rats. Alcohol. Clin. Exp. Res.
21(6): 1042-1046.

Jamincky, B., Muck-Seler, D., and Slijepcevic, M. 1993. Favourable effect of (AC)/
insulin treatment on serotoninergic imbalance in alloxan diabetic rats. Comp.
Biochem. Physiol 105A(2):267-273.

Jeejeebhoy, K.N., Chu, R.C., Marliss, E.B., and Greenberg, G.R. 1977.
(AC) deficiency, glucose intolerance, and neuropathy reversed by (AC) supplementation
in a patient receiving long-term total parenteral nutrition.
Am. J. Clin. Nutr. 30:531-538.

Jeejeebhoy, K.N. 1999. The role of (AC) in nutrition and therapeutics and as a potential
toxin. Nutr. Rev. 57(11):329-335.

Josey, E.S. and Tacket, R.L. 1999. (HH): a new alternative for depression? Int. J. Clin.
Pharmacol. Ther. 37(3): 111-119.
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June, H.L., Hughes, R.W., Spurlock, H.L., and Lewis, M.J. 1994. Ethanol
self-administration in freely feeding and drinking rats: effects of Ro 15-4513 alone,
and in combination with Ro 15-1788 (HH). Psychopharmacology 115:332-339.

Kerai, M.D., Waterfield, C.J., Kenyon, S.H., Asker, D.S., and Timbrell, J.A. 1999.
Reversal of ethanol-induced hepatic steatosis and lipid peroxidation by (AC): a
study in rats. Alcohol Alcohol. 34(4):529-41.

Keung, W-M. and Vallee, B.L. 1993a. (AC) and (AC) suppress free-choice ethanol
intake by Syrian golden hamsters. Proc. Natl. Acad. Sci. 90:10008-10012.

Keung, W-M. and Vallee, B.L. 1993b. (AC): A potent, selective inhibitor of human
mitochondrial aldehyde dehydrogenase. Proc. Natl. Acad. Sci. 90:1247-1251.

Keung, W-M, Lazo, 0., Kunze, L., and Vallee, B.L. 1996. Potentiation of the
bioavailability of (AC) by an extract of (AC). Proc. Natl. Acad. Sci. 93:4284-4288.

Keung, W-M. and Vallee, B.L. 1998a. (AC) root: An ancient Chinese source of
modem antidipsotropic agents. Phytochem. 47(4):499-506.

Keung, W-M. and Vallee, B.L. 1998b. (AC) and its antidipsotropic analogs inhibit
serotonin and dopamine metabolism in isolated mitochondria. Proc. Natl. Acad. Sci.
95:2198-2203.

Kontro, P., Korpi, E.R., and Oja, S.S. 1990. (AC) interacts with GABAa and GABAn
receptors in the brain. Prog. Clin. Biol. Res. 351:83-94.

Koob, G.F., Sanna, P.P., and Bloom, F.E. 1998. Neuroscience of addiction. Neuron.
21:467- 476.

Korf, J., Venema, K., and Postema, F. 1974. Decarboxylation of exogenous 1-5-
(AC) after destruction of cerebral raphe system. J. Neurochem. 00:000-000
(as cited in Byerley 1987).

Kostowski, W. and Bienkowski P. 1999. Discriminative stimulus effects of ethanol:
Neuropharmacological characterization. Alcohol. 17(1):63-80.

Lenoir, S., Degenring, F.H., and Sailer, R. 1999. A double-blind randomized trial to
investigate three different concentrations of a standardized fresh plant extract
obtained from the shoot tips of (AC) L. Phytomed. 6(3): 141-146.
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